There are many experts trying to identify the “next big thing” in corporate philanthropy, from “collaborative social initiatives” to “corporate social marketing.” Each of these new strategies are important, but they rarely recognize the full range of philanthropic options available to a business, or the internal motivations and external contexts that can guide a company’s charitable choices. This paper, adapted from the Monitor Institute presentation for the Opening Session for Corporate Grantmakers at the Council on Foundations 2006 Annual Conference, provides a high-level conceptual framework to help corporate foundations understand the array of options that are available for their giving, and how uncertainties in the world around their companies might influence their choices.